Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.36 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24853071 | 0.89 | MAPT (0.36) | MAPTTHRBKMT2ATGFBR1TP53 | |
| SCHEMBL29065076 | 0.86 | MAPT (0.38) | MAPTTHRBKMT2AMEN1LMNA | |
| SCHEMBL29065022 | 0.77 | CYP2D6 (0.39) | MAPTTHRBKMT2AMEN1LMNA | |
| SCHEMBL24035973 | 0.76 | MAPT (0.37) | MAPTTHRBKMT2ATP53 | |
| SCHEMBL24852871 | 0.76 | MAPT (0.36) | MAPTTHRBKMT2AMEN1LMNA | |
| SCHEMBL24853073 | 0.76 | MAPT (0.38) | MAPTTHRBKMT2AMEN1LMNA | |
| SCHEMBL26627925 | 0.76 | MAPT (0.38) | MAPTTHRBLMNATP53ALDH1A1 | |
| SCHEMBL29065124 | 0.74 | MAPT (0.36) | MAPTTHRBKMT2AMEN1LMNA | |
| SCHEMBL26756814 | 0.73 | MAPT (0.32) | MAPTTHRBTP53 | |
| SCHEMBL29064987 | 0.73 | IRAK4 (0.32) | MAPTTHRBKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |