Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24035241 | 0.85 | CYP2D6 (0.43) | CYP2D6CYP1A2HDAC6HDAC10MAPT | |
| SCHEMBL24035200 | 0.85 | CYP2D6 (0.40) | CYP2D6CYP1A2HDAC6HDAC10MAPT | |
| SCHEMBL29065088 | 0.81 | CYP2D6 (0.32) | CYP2D6CYP1A2BRD4 | |
| SCHEMBL29065003 | 0.80 | FFAR1 (0.33) | MAPTTSHRMEN1KMT2ATP53 | |
| SCHEMBL29065110 | 0.78 | NOTUM (0.34) | ALDH1A1 | |
| SCHEMBL29064985 | 0.77 | MAPT (0.36) | MAPTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL29065052 | 0.75 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL26735719 | 0.75 | CYP2D6 (0.41) | CYP2D6CYP1A2HDAC6HDAC10MAPT | |
| SCHEMBL24036289 | 0.75 | CYP2D6 (0.38) | CYP2D6CYP1A2HDAC6HDAC10MAPT | |
| SCHEMBL29065124 | 0.74 | MAPT (0.36) | MAPTTSHRMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |