Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | LGMN | Q99538 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177428 | 0.83 | KMT2A (0.40) | KIF11KMT2AMEN1ELANEPOLB | |
| SCHEMBL28292591 | 0.81 | KIF11 (0.39) | KIF11KMT2AMEN1ELANEPOLB | |
| SCHEMBL19251760 | 0.78 | CHRNA7 (0.38) | CHRNA7 | |
| SCHEMBL4762723 | 0.76 | KIF11 (0.51) | KIF11KMT2AMEN1 | |
| SCHEMBL15881209 | 0.74 | KMT2A (0.41) | KIF11KMT2AMEN1POLBJAK2 | |
| SCHEMBL28826166 | 0.73 | CYP1A2 (0.35) | CHRNA7ELANECYP2C19BRAFMTOR | |
| SCHEMBL25295915 | 0.72 | CHRNA7 (0.44) | CHRNA7KMT2AMEN1BRAFJAK2 | |
| SCHEMBL30521483 | 0.72 | CHRNA7 (0.44) | CHRNA7KMT2AMEN1BRAFJAK2 | |
| SCHEMBL9413732 | 0.71 | KMT2A (0.55) | KIF11KMT2AMEN1 | |
| SCHEMBL30566578 | 0.71 | KMT2A (0.55) | KIF11KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |