Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 4/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177428 | 0.88 | KMT2A (0.40) | KIF11KMT2AMEN1ELANEADAMTS4 | |
| SCHEMBL29065136 | 0.81 | CHRNA7 (0.43) | KIF11KMT2AMEN1ELANEADAMTS4 | |
| SCHEMBL4762723 | 0.81 | KIF11 (0.51) | KIF11KMT2AMEN1SCN9AMRGPRX4 | |
| SCHEMBL28940966 | 0.77 | MEN1 (0.38) | KIF11KMT2AMEN1 | |
| SCHEMBL17966038 | 0.77 | PDE10A (0.40) | CYP2C19PKMTGFBR1ALOX5APALDH1A1 | |
| SCHEMBL28292573 | 0.76 | KIF11 (0.36) | KIF11KMT2AMEN1ELANESCN9A | |
| SCHEMBL28817265 | 0.75 | MEN1 (0.46) | KIF11KMT2AMEN1TGFBR1 | |
| SCHEMBL9413732 | 0.75 | KMT2A (0.55) | KIF11KMT2AMEN1MAPT | |
| SCHEMBL30566578 | 0.75 | KMT2A (0.55) | KIF11KMT2AMEN1MAPT | |
| SCHEMBL6218239 | 0.75 | TGFBR1 (0.34) | ELANECYP2C19SCN9ATGFBR1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |