Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 5/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068108 | 0.92 | ANPEP (0.33) | ALOX5SLC1A3SLC1A2SLC1A1CTSK | |
| SCHEMBL29068106 | 0.92 | ANPEP (0.33) | ALOX5SLC1A3SLC1A2SLC1A1CTSK | |
| SCHEMBL28821271 | 0.86 | ANPEP (0.30) | ANPEP | |
| SCHEMBL28821269 | 0.86 | ANPEP (0.30) | ANPEP | |
| SCHEMBL9219383 | 0.81 | ANPEP (0.38) | ANPEP | |
| SCHEMBL29067935 | 0.77 | ANPEP (0.33) | ALOX5SLC1A3SLC1A2SLC1A1CTSK | |
| SCHEMBL29067937 | 0.77 | ANPEP (0.33) | ALOX5SLC1A3SLC1A2SLC1A1CTSK | |
| SCHEMBL2480097 | 0.75 | — | — | |
| SCHEMBL19385501 | 0.74 | CTSK (0.42) | CTSKCTSLCTSBEPHX1 | |
| SCHEMBL28376567 | 0.73 | SLC1A3 (0.37) | ALOX5SLC1A3SLC1A2SLC1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111171047-B | Fused dihydro-4H-pyrazolo [5,1-C ] [1,4] oxazinyl compounds for the treatment of CNS disorders | 赛诺维信制药公司 | 2023-06-23 | — | — | CN | disclosed |