Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 4/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388517 | 0.95 | CTSK (0.40) | SLC1A3SLC1A2SLC1A1CTSKCTSL | |
| SCHEMBL29214288 | 0.93 | ANPEP (0.36) | SLC1A3SLC1A2SLC1A1CTSKCTSL | |
| SCHEMBL29214297 | 0.93 | ANPEP (0.36) | SLC1A3SLC1A2SLC1A1CTSKCTSL | |
| SCHEMBL29065552 | 0.73 | ALOX5 (0.36) | SLC1A3SLC1A2SLC1A1CTSKCTSL | |
| SCHEMBL30890796 | 0.70 | CTSK (0.37) | CTSKCTSLCTSBCTSHANPEP | |
| SCHEMBL7378597 | 0.70 | — | — | |
| SCHEMBL8283422 | 0.70 | — | — | |
| SCHEMBL10077598 | 0.70 | — | — | |
| SCHEMBL28645329 | 0.69 | LMNA (0.31) | — | |
| SCHEMBL21876522 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111171047-A | Fused dihydro-4H-pyrazolo [5,1-C ] [1,4] oxazinyl compounds for the treatment of CNS disorders | 赛诺维信制药公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-107567454-B | Fused dihydro-4H-pyrazolo [5,1-C ] [1,4] oxazinyl compounds and analogs thereof for the treatment of CNS disorders | 赛诺维信制药公司 | 2020-02-18 | — | — | CN | disclosed |