Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2210266 | 0.88 | BRD4 (0.44) | BRD4EPHX1EPHX2SMN1; SMN2POLB | |
| SCHEMBL3956402 | 0.82 | MGAM (0.42) | BRD4EPHX1EPHX2SMN1; SMN2KMT2A | |
| SCHEMBL4243752 | 0.80 | KDM4E (0.49) | EPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28055530 | 0.78 | MGAM (0.39) | BRD4EPHX1EPHX2ALDH1A1KMT2A | |
| SCHEMBL1015355 | 0.78 | KMT2A (0.42) | EPHX1EPHX2POLBALDH1A1KMT2A | |
| SCHEMBL28718093 | 0.78 | BRD4 (0.45) | BRD4EPHX1EPHX2SMN1; SMN2POLB | |
| SCHEMBL27157599 | 0.78 | BRD4 (0.45) | BRD4EPHX1EPHX2SMN1; SMN2POLB | |
| SCHEMBL4127454 | 0.78 | ALDH1A1 (0.47) | EPHX1EPHX2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL22750444 | 0.78 | BRD4 (0.45) | BRD4EPHX1EPHX2SMN1; SMN2POLB | |
| SCHEMBL909706 | 0.77 | EPHX1 (0.46) | EPHX1EPHX2POLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217569-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | Janssen Pharmaceutica N.V. (BE) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009058314-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |