SCHEMBL29065638

SCHEMBL29065638

CC(C)(C)COP(O)Oc1c(C(C)(C)C)cccc1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
ALDH1A1 P00352 5/20 0.35
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
GAA P10253 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NAMPT P43490 1/20 0.32
NLRP3 Q96P20 1/20 0.31
SCN2A Q99250 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4456194 0.86 CA2 (0.35) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL5437245 0.84 CA2 (0.48) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL11342646 0.83 CYP2D6 (0.36) GABRA1GABRB2ALDH1A1TSHRGAA
SCHEMBL5341240 0.82 MAPT (0.39) ALDH1A1TSHRTDP1GAAKDM4E
Fluoromethane SCHEMBL9702099 0.80 CA2 (0.45) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL8389885 0.77 GABRA1 (0.50) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL8394955 0.77 CA2 (0.42) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL1649534 0.76 CA2 (0.48) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL31376369 0.76 CA2 (0.41) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL2379764 0.74 RIPK1 (0.36) ALDH1A1TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114426761-B Biodegradable polyester material and method for producing same 财团法人工业技术研究院 2023-09-08 CN disclosed