Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839103 | 0.85 | MAPK1 (0.57) | TSHRMAPK1LMNAMAPTCA12 | |
| SCHEMBL29065716 | 0.84 | LMNA (0.52) | TSHRMAPK1LMNAMAPTNPSR1 | |
| SCHEMBL7312805 | 0.81 | LMNA (0.71) | TSHRMAPK1LMNAMAPTNPSR1 | |
| SCHEMBL17399834 | 0.81 | CYP2C19 (0.53) | MAPK1KDM4EHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL16407064 | 0.81 | HSD17B10 (0.61) | TSHRMAPK1LMNAMAPTNPSR1 | |
| SCHEMBL9377084 | 0.78 | POLB (0.54) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14855710 | 0.77 | KDM4E (0.71) | TSHRMAPK1LMNANPSR1TP53 | |
| SCHEMBL4026343 | 0.76 | LMNA (0.53) | TSHRMAPK1LMNAMAPTCA12 | |
| SCHEMBL31590548 | 0.76 | LMNA (0.53) | TSHRMAPK1LMNAMAPTCA12 | |
| SCHEMBL28061271 | 0.76 | TSHR (0.56) | TSHRLMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368749-B1 | Substituted carboxylic acid, and their production and use | SUMITOMO CHEMICAL CO (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5049575-A | Substituted carboxylic acid, fungicidal compositions and use | SUMITOMO CHEMICAL COMPANY (JP) | 1991-09-17 | — | — | US | disclosed |
| EP-0368749-A1 | Substituted carboxylic acid, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-05-16 | — | — | EP | disclosed |