Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399590 | 0.92 | ALDH1A1 (0.49) | ALDH1A1LMNADRD2MAPTSMN1; SMN2 | |
| SCHEMBL29065776 | 0.91 | ADAM10 (0.50) | ALDH1A1LMNADRD2FFAR4MAPT | |
| SCHEMBL29065775 | 0.90 | MAPT (0.47) | ALDH1A1LMNADRD2MAPTSMN1; SMN2 | |
| SCHEMBL29397041 | 0.89 | DRD2 (0.45) | ALDH1A1LMNADRD2FFAR4MAPT | |
| SCHEMBL13419583 | 0.88 | ALDH1A1 (0.58) | ALDH1A1LMNADRD2MAPTSMN1; SMN2 | |
| SCHEMBL29399554 | 0.87 | MAPT (0.56) | ALDH1A1LMNADRD2MAPTSMN1; SMN2 | |
| SCHEMBL29400399 | 0.85 | FFAR4 (0.57) | ALDH1A1LMNAFFAR4MAPTSMN1; SMN2 | |
| SCHEMBL22246076 | 0.85 | ALDH1A1 (0.43) | ALDH1A1DRD2MAPTSMN1; SMN2GAA | |
| SCHEMBL29783035 | 0.82 | MAPT (0.42) | ALDH1A1LMNADRD2MAPTSMN1; SMN2 | |
| SCHEMBL28645572 | 0.82 | ADAM10 (0.47) | ALDH1A1LMNADRD2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302196-B | EGFR inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| US-20220064196-A1 | EGFR Inhibitors, Compositions and Methods Thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2022-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064196-A1 | EGFR Inhibitors, Compositions and Methods Thereof | EGFR, ERBB2, ERBB3 | ALDH1A1 3755/4885LMNA 3691/4885DRD2 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.