SCHEMBL29065876

SCHEMBL29065876

Cc1ccc(C(=O)NC(c2ccc(Br)cc2)C2CCCCC2=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
MAPT P10636 2/20 0.52
NPSR1 Q6W5P4 1/20 0.52
ALDH1A1 P00352 3/20 0.46
GAA P10253 2/20 0.46
HSP90AA1 P07900 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP3A4 P08684 2/20 0.44
TSHR P16473 2/20 0.44
SMN1; SMN2 Q16637 4/20 0.43
CA1 P00915 1/20 0.43
MCHR1 Q99705 3/20 0.42
HPGD P15428 4/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
POLB P06746 1/20 0.41
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29065879 0.88 CA1 (0.56) LMNAMAPTNPSR1ALDH1A1GAA
SCHEMBL29065898 0.88 LMNA (0.47) LMNAMAPTNPSR1ALDH1A1GAA
SCHEMBL29065882 0.82 LMNA (0.42) LMNAMAPTNPSR1ALDH1A1GAA
SCHEMBL29065873 0.81 MAPT (0.77) LMNAMAPTNPSR1GAASMN1; SMN2
SCHEMBL29065886 0.81 S1PR1 (0.47) LMNAMAPTALDH1A1SMN1; SMN2CA1
SCHEMBL29065874 0.77 RAB9A (0.44) LMNAALDH1A1GAAKMT2ASMN1; SMN2
SCHEMBL29065864 0.75 CA1 (0.61) LMNAMAPTALDH1A1GAAKMT2A
SCHEMBL29065872 0.71 MAPT (0.90) LMNAMAPTNPSR1ALDH1A1SMN1; SMN2
SCHEMBL30960329 0.70 MAPT (0.55) LMNAMAPTNPSR1ALDH1A1CYP3A4
SCHEMBL14292319 0.70 MAPT (0.55) LMNAMAPTNPSR1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715596-A Method for synthesizing beta-aminoketone compound by synergistic catalysis of cyclopentadienyl titanium/Bronsted acid 宁夏师范学院 2023-09-08 CN disclosed