SCHEMBL29065879

SCHEMBL29065879

Cc1ccc(C(=O)NC(c2ccccc2)C2CCCCC2=O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.56
LMNA P02545 4/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
MAPT P10636 3/20 0.51
HPGD P15428 2/20 0.51
KDM4E B2RXH2 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
TP53 P04637 1/20 0.48
ALDH1A1 P00352 6/20 0.47
MEN1 O00255 1/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 1/20 0.45
HTR1E P28566 1/20 0.44
S1PR3 Q99500 1/20 0.44
CYP1A2 P05177 4/20 0.44
CYP2C9 P11712 3/20 0.44
CYP2C19 P33261 3/20 0.44
CYP3A4 P08684 3/20 0.44
TSHR P16473 3/20 0.44
CYP2D6 P10635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29065876 0.88 LMNA (0.52) CA1LMNASMN1; SMN2MAPTHPGD
SCHEMBL29065898 0.88 LMNA (0.47) CA1LMNASMN1; SMN2MAPTHPGD
SCHEMBL29065886 0.87 S1PR1 (0.47) CA1LMNASMN1; SMN2MAPTHPGD
SCHEMBL29065882 0.84 LMNA (0.42) CA1LMNASMN1; SMN2MAPTHPGD
SCHEMBL29065874 0.83 RAB9A (0.44) CA1LMNASMN1; SMN2HPGDALDH1A1
SCHEMBL29065864 0.81 CA1 (0.61) CA1LMNASMN1; SMN2MAPTHPGD
SCHEMBL29065875 0.80 CA1 (0.82) CA1LMNASMN1; SMN2MAPTHPGD
SCHEMBL28015291 0.78 CA1 (0.82) CA1LMNASMN1; SMN2MAPTHPGD
SCHEMBL6818965 0.73 SLC6A9 (0.62) LMNAMAPTALDH1A1MEN1MAPK1
SCHEMBL16375340 0.72 CA1 (1.00) CA1LMNASMN1; SMN2MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715596-A Method for synthesizing beta-aminoketone compound by synergistic catalysis of cyclopentadienyl titanium/Bronsted acid 宁夏师范学院 2023-09-08 CN disclosed