SCHEMBL29065941

SCHEMBL29065941

C=Cc1ccc(-c2ccc(N)c(-c3ccc(C=C)cc3)c2N)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
HDAC2 Q92769 1/20 0.36
DAPK3 O43293 1/20 0.34
JAK2 O60674 1/20 0.34
ABL1 P00519 1/20 0.34
NTRK1 P04629 1/20 0.34
FYN P06241 1/20 0.34
CSF1R P07333 1/20 0.34
RET P07949 1/20 0.34
MET P08581 1/20 0.34
PDGFRB P09619 1/20 0.34
FGFR1 P11362 1/20 0.34
FLT3 P36888 1/20 0.34
MAPK8 P45983 1/20 0.34
GSK3B P49841 1/20 0.34
CDK9 P50750 1/20 0.34
RPS6KA3 P51812 1/20 0.34
LIMK1 P53667 1/20 0.34
MAP2K1 Q02750 1/20 0.34
NTRK3 Q16288 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648324 0.81 ALDH1A1 (0.39) ALDH1A1HDAC2DAPK3JAK2ABL1
SCHEMBL29065939 0.80 ALDH1A1 (0.46) ALDH1A1HDAC2DAPK3JAK2ABL1
SCHEMBL28466430 0.77 ALDH1A1 (0.42) ALDH1A1HDAC2DAPK3JAK2ABL1
SCHEMBL16174757 0.77 ALDH1A1 (0.42) ALDH1A1HDAC2DAPK3JAK2ABL1
SCHEMBL1900832 0.76 PTGS2 (0.38) ALDH1A1TSHRTDP1
SCHEMBL904407 0.75 ALDH1A1 (0.50) ALDH1A1TDP1
SCHEMBL23464382 0.74 ALDH1A1 (0.44) ALDH1A1HDAC2DAPK3JAK2ABL1
SCHEMBL30560581 0.74 ALDH1A1 (0.48) ALDH1A1HDAC2DAPK3JAK2ABL1
SCHEMBL6571378 0.73 ALDH1A1 (0.42) ALDH1A1HDAC2DAPK3JAK2ABL1
SCHEMBL28694640 0.72 KDM4E (0.39) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715594-B Star-shaped micromolecule crosslinked hole transport material and preparation method and application thereof 天津大学 2023-12-15 CN disclosed
CN-116715594-A Star-shaped micromolecule crosslinked hole transport material and preparation method and application thereof 天津大学 2023-09-08 CN disclosed