SCHEMBL1900832

SCHEMBL1900832

Cc1ccc(-c2ccc(N)c(-c3ccc(C)cc3)c2N)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.38
PTGS1 P23219 2/20 0.38
TDP1 Q9NUW8 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CYP3A4 P08684 2/20 0.38
TP53 P04637 1/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
ACHE P22303 2/20 0.37
ALDH1A1 P00352 4/20 0.37
TSHR P16473 3/20 0.37
USP7 Q93009 2/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HEXA P06865 1/20 0.36
HEXB P07686 1/20 0.36
MAPK1 P28482 4/20 0.35
KDM4E B2RXH2 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1712808 0.83 PTGS2 (0.41) PTGS2PTGS1TDP1SMN1; SMN2CYP3A4
SCHEMBL7499973 0.83 TDP1 (0.41) PTGS2PTGS1TDP1SMN1; SMN2CYP3A4
SCHEMBL1263497 0.83 PTGS2 (0.44) PTGS2PTGS1TDP1SMN1; SMN2ACHE
SCHEMBL353048 0.83 TDP1 (0.41) PTGS2PTGS1TDP1SMN1; SMN2CYP3A4
SCHEMBL4248242 0.82 TDP1 (0.48) TDP1SMN1; SMN2CYP3A4TP53THRB
SCHEMBL13515175 0.82 ACHE (0.48) PTGS2PTGS1TDP1SMN1; SMN2ACHE
SCHEMBL28975154 0.82 CNR1 (0.38) PTGS2TDP1SMN1; SMN2CYP3A4TP53
SCHEMBL29287632 0.81 TDP1 (0.44) TDP1SMN1; SMN2CYP3A4TP53THRB
SCHEMBL8573252 0.80 ADORA2A (0.42) PTGS2PTGS1TDP1SMN1; SMN2ALDH1A1
SCHEMBL3468830 0.80 ACHE (0.50) PTGS2PTGS1TDP1SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116987108-A Polycyclic aromatic compound, material for organic element, composition for forming light-emitting layer, organic electroluminescent element, and device 学校法人关西学院 2023-11-03 CN disclosed
US-20200190115-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-06-18 US disclosed
EP-3626722-A1 POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2020-03-25 EP disclosed
CN-110612304-A Polycyclic aromatic compound 学校法人关西学院 2019-12-24 CN disclosed
WO-2011055932-A9 ORGANIC COMPOUND, ORGANIC ELECTRONIC DEVICE USING SAME, AND TERMINAL FOR SAME 덕산하이메탈(주) (KR) 2011-09-01 WO disclosed
WO-2011055932-A2 ORGANIC COMPOUND, ORGANIC ELECTRONIC DEVICE USING SAME, AND TERMINAL FOR SAME 덕산하이메탈(주) (KR) 2011-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190115-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC PTGS2 4452/4885PTGS1 4573/4885TDP1 2238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.