Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13499160 | 0.77 | CA2 (0.41) | SLC6A2SLC6A3SLC6A4HTR2A | |
| SCHEMBL2906600 | 0.77 | CA2 (0.41) | SLC6A2SLC6A3SLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL1002826 | 0.76 | CA2 (0.42) | — | |
| SCHEMBL14275866 | 0.70 | ADRA1D (0.34) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL6924410 | 0.69 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4HTR2A | |
| SCHEMBL6223726 | 0.67 | ESR2 (0.34) | MEN1KMT2A | |
| SCHEMBL4053422 | 0.66 | HAO1 (0.39) | MEN1KMT2A | |
| SCHEMBL10192537 | 0.64 | SLC6A2 (0.38) | SLC6A2SLC6A3SLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL30989920 | 0.63 | SLC6A2 (0.37) | SLC6A2SLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL30989811 | 0.63 | SLC6A2 (0.37) | SLC6A2SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825253-B2 | 2-aminoquinoline derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-11-02 | — | — | US | disclosed |
| EP-2076495-B1 | QUINOLINE DERIVATIVES WITH 5-HT-BINDING PROPERTIES | HOFFMANN LA ROCHE (CH) | 2010-08-18 | — | — | EP | disclosed |
| US-20080081907-A1 | 2-AMINOQUINOLINE DERIVATIVES | HOFFMANN-LA ROCHE INC. | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081907-A1 | 2-AMINOQUINOLINE DERIVATIVES | AR, ADRA2C, RCC2 | SLC6A2 449/4885SLC6A3 1427/4885SLC6A4 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.