Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 17/20 | 0.41 |
| ▸ | THRA | P10827 | 16/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30083009 | 0.83 | THRB (0.40) | THRBTHRARORC | |
| SCHEMBL29527525 | 0.79 | THRB (0.38) | THRBTHRARORC | |
| SCHEMBL24407952 | 0.77 | THRB (0.65) | THRBTHRARORC | |
| SCHEMBL22632428 | 0.76 | THRA (0.66) | THRBTHRA | |
| SCHEMBL24407918 | 0.72 | THRB (0.40) | THRBTHRARORC | |
| SCHEMBL24407975 | 0.72 | THRB (0.70) | THRBTHRA | |
| SCHEMBL24408068 | 0.72 | THRA (0.45) | THRBTHRA | |
| SCHEMBL29527567 | 0.72 | THRA (0.39) | THRBTHRA | |
| SCHEMBL24407919 | 0.71 | THRB (0.70) | THRBTHRA | |
| SCHEMBL24407897 | 0.71 | THRB (0.69) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240730-A1 | 2-PYRIDONES AS THYROID HORMONE RECEPTOR MODULATORS | Aligos Therapeutics, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| CN-116710443-A | 2-pyridones as thyroid hormone receptor modulators | 阿利戈斯治疗公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2022099044-A1 | 2-PYRIDONES AS THYROID HORMONE RECEPTOR MODULATORS | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |