Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 17/20 | 0.40 |
| ▸ | THRA | P10827 | 15/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655436 | 0.84 | THRA (0.44) | THRBTHRA | |
| SCHEMBL29066180 | 0.83 | THRB (0.41) | THRBTHRARORC | |
| SCHEMBL29527525 | 0.82 | THRB (0.38) | THRBTHRARORC | |
| SCHEMBL24407897 | 0.79 | THRB (0.69) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL24407952 | 0.78 | THRB (0.65) | THRBTHRARORC | |
| SCHEMBL29527154 | 0.78 | THRB (0.39) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL29527283 | 0.75 | THRB (0.48) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL24407975 | 0.75 | THRB (0.70) | THRBTHRACYP2C9UGT1A1ABCG2 | |
| SCHEMBL23168952 | 0.75 | THRB (0.34) | THRBTHRA | |
| SCHEMBL24408068 | 0.75 | THRA (0.45) | THRBTHRACYP2C9UGT1A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710443-A | 2-pyridones as thyroid hormone receptor modulators | 阿利戈斯治疗公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-113698388-B | 6-oxo-1, 6-dihydropyridine derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |