Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24330030 | 0.85 | POLB (0.61) | KMT2AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL30660067 | 0.79 | MEN1 (0.50) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL8011548 | 0.79 | MEN1 (0.50) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL26691523 | 0.78 | KDM4E (0.52) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL9290373 | 0.75 | MEN1 (0.67) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL27856264 | 0.73 | NTRK1 (0.67) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL11181448 | 0.72 | KDM4E (0.79) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL29583059 | 0.70 | CTRB1 (0.47) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL24330033 | 0.70 | CTRB1 (0.47) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL4582152 | 0.70 | MEN1 (0.82) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116723839-A | Tricyclic heterobifunctional compounds for degrading target proteins | C4医药公司 | 2023-09-08 | — | — | CN | disclosed |