Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30660067 | 1.00 | MEN1 (0.50) | MEN1KMT2AL3MBTL1CA12CA9 | |
| SCHEMBL3441080 | 0.87 | CDC25A (0.51) | MEN1KMT2AL3MBTL1CA12CA9 | |
| SCHEMBL7402520 | 0.81 | CA12 (0.53) | MEN1KMT2AL3MBTL1CA12CA9 | |
| SCHEMBL11408828 | 0.79 | NTRK1 (0.52) | MEN1KMT2AL3MBTL1CA12CA9 | |
| SCHEMBL6150350 | 0.79 | ALDH1A1 (0.45) | MEN1KMT2AL3MBTL1CA12CA9 | |
| SCHEMBL29066255 | 0.79 | KMT2A (0.51) | MEN1KMT2AL3MBTL1KDM4EPOLB | |
| SCHEMBL8873486 | 0.77 | CYP1A2 (0.48) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL4813089 | 0.76 | MAPT (0.45) | MEN1KMT2AL3MBTL1CA12CA9 | |
| SCHEMBL8482005 | 0.76 | HDAC8 (0.44) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL31526985 | 0.76 | CYP1A2 (0.47) | MEN1KMT2AL3MBTL1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6056939-A | Self-assembling heteropolymetallic chelates as imaging agents and radiopharmaceuticals | BRACCO IMAGING S.P.A. (IT) | 2000-05-02 | — | — | US | disclosed |