SCHEMBL29066337

SCHEMBL29066337

CN(C)CCCc1nc(CCCN(C)C)nc(CCCN(C)C)n1.[H+]

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
NOS3 P29474 4/20 0.41
NOS1 P29475 4/20 0.41
NOS2 P35228 2/20 0.41
DNM1 Q05193 3/20 0.36
SIGMAR1 Q99720 1/20 0.35
HRH4 Q9H3N8 2/20 0.35
HRH3 Q9Y5N1 2/20 0.35
CASP1 P29466 1/20 0.35
TLR8 Q9NR97 1/20 0.34
TLR7 Q9NYK1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5718810 0.97 ALDH1A1 (0.45) ALDH1A1TSHRNOS3NOS1NOS2
SCHEMBL9414092 0.80 TAAR1 (0.40) ALDH1A1TSHRNOS3NOS1NOS2
SCHEMBL27328050 0.73 NOS3 (0.49) ALDH1A1TSHRNOS3NOS1NOS2
SCHEMBL930197 0.72 HRH3 (0.39) ALDH1A1TSHRNOS3NOS1NOS2
SCHEMBL12330071 0.71 NOS1 (0.40) ALDH1A1TSHRNOS3NOS1NOS2
SCHEMBL522952 0.67 KCNH2 (0.55) NOS3NOS1NOS2SIGMAR1
SCHEMBL1290871 0.65 ALDH1A1 (0.75) ALDH1A1TSHRDNM1SIGMAR1HRH4
SCHEMBL21216 0.65 ALDH1A1 (0.91) ALDH1A1TSHRDNM1SIGMAR1
SCHEMBL212626 0.65
SCHEMBL9333223 0.65 ALDH1A1 (0.53) ALDH1A1TSHRDNM1SIGMAR1HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112204064-B Adducts of amine catalysts for the production of isocyanurate polymers 科思创知识产权两合公司 2023-07-28 CN disclosed
CN-116472300-A Reaction mixture for producing foams based on inorganic fillers comprising closed-cell rigid polyurethane or polyisocyanurate 亨斯迈国际有限责任公司 2023-07-21 CN disclosed
CN-112020525-B Adducts of amine catalysts for preparing isocyanurate polymers 科思创知识产权两合公司 2023-05-16 CN disclosed