Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | LCK | P06239 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.63 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.63 |
| ▸ | BCL2 | P10415 | 4/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16227041 | 0.88 | MAPT (0.68) | MAPTALDH1A1LCKGLATHRB | |
| SCHEMBL18601895 | 0.86 | MAPT (0.65) | MAPTALDH1A1LCKGLATHRB | |
| SCHEMBL8341400 | 0.83 | MAPT (0.69) | MAPTALDH1A1LCKGLATHRB | |
| SCHEMBL3174840 | 0.80 | BCL2 (0.71) | MAPTALDH1A1LCKGLATHRB | |
| SCHEMBL19461410 | 0.79 | MAPT (0.61) | MAPTALDH1A1LCKGLATHRB | |
| 2-Methoxyanthraquinone SCHEMBL28176342 | 0.79 | MAPT (0.50) | MAPTALDH1A1LCKGLATHRB | |
| SCHEMBL4460906 | 0.78 | BCL2 (0.44) | MAPTALDH1A1LCKGLATHRB | |
| SCHEMBL6361693 | 0.78 | EPHX2 (0.67) | MAPTALDH1A1LCKGLATHRB | |
| SCHEMBL3191867 | 0.78 | EPHX2 (0.57) | MAPTALDH1A1LCKGLATHRB | |
| Damnacanthol SCHEMBL16225889 | 0.78 | MAPT (0.63) | MAPTALDH1A1LCKGLATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115245533-B | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | claimed |
| CN-116585295-A | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-08-15 | — | — | CN | disclosed |
| CN-115245533-B | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | disclosed |