Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 3/20 | 0.40 |
| ▸ | PKLR | P30613 | 6/20 | 0.39 |
| ▸ | PGAM1 | P18669 | 4/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455117 | 0.89 | MEN1 (0.50) | MAPTALDH1A1THRBTTRELANE | |
| SCHEMBL4453646 | 0.85 | NPC1 (0.43) | MCL1MAPTALDH1A1LCKGLA | |
| SCHEMBL2955404 | 0.80 | BCL2 (0.47) | BCL2MCL1MAPTALDH1A1LCK | |
| SCHEMBL29066464 | 0.78 | MAPT (0.63) | BCL2MCL1MAPTALDH1A1LCK | |
| SCHEMBL4455628 | 0.75 | ELANE (0.47) | MAPTALDH1A1TTRELANEMEN1 | |
| SCHEMBL13742921 | 0.74 | MAPT (0.51) | MAPTALDH1A1THRBTTRPDK4 | |
| SCHEMBL4463498 | 0.72 | RAB9A (0.40) | MCL1MAPTALDH1A1LCKGLA | |
| SCHEMBL3174840 | 0.72 | BCL2 (0.71) | BCL2MCL1MAPTALDH1A1LCK | |
| SCHEMBL8976133 | 0.70 | MAPT (0.40) | BCL2MCL1MAPTALDH1A1LCK | |
| SCHEMBL2957671 | 0.70 | MAPT (0.44) | MAPTALDH1A1LCKGLATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010474-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | Sanofi-Aventis (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007121822-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | SANOFI-AVENTIS (DE) | 2007-11-01 | — | — | WO | disclosed |