Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30421200 | 1.00 | KDM4E (0.60) | KDM4EMEN1KMT2ATDP1NPC1 | |
| SCHEMBL29066490 | 1.00 | KDM4E (0.60) | KDM4EMEN1KMT2ATDP1NPC1 | |
| SCHEMBL29066494 | 0.84 | MAPT (0.61) | KDM4EMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL29066493 | 0.84 | MAPT (0.61) | KDM4EMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL29066479 | 0.82 | RAB9A (0.48) | MEN1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL29066482 | 0.82 | RAB9A (0.48) | MEN1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL29066480 | 0.82 | MAPT (0.48) | KDM4EMEN1KMT2ATDP1NPC1 | |
| SCHEMBL29066478 | 0.82 | MAPT (0.48) | KDM4EMEN1KMT2ATDP1NPC1 | |
| SCHEMBL30421177 | 0.82 | MAPT (0.48) | KDM4EMEN1KMT2ATDP1NPC1 | |
| SCHEMBL10127235 | 0.78 | MEN1 (0.67) | KDM4EMEN1KMT2ATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283822-A | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116283822-A | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2023-06-23 | — | — | CN | disclosed |