Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | GUSB | P08236 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29066494 | 1.00 | MAPT (0.61) | MAPTPSMD14POLBRAB9ACYP1A2 | |
| SCHEMBL30421177 | 0.88 | MAPT (0.48) | MAPTPSMD14POLBRAB9ACYP1A2 | |
| SCHEMBL29066478 | 0.88 | MAPT (0.48) | MAPTPSMD14POLBRAB9ACYP1A2 | |
| SCHEMBL29066480 | 0.88 | MAPT (0.48) | MAPTPSMD14POLBRAB9ACYP1A2 | |
| SCHEMBL29066492 | 0.84 | KDM4E (0.60) | MAPTRAB9ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL30421200 | 0.84 | KDM4E (0.60) | MAPTRAB9ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL29066490 | 0.84 | KDM4E (0.60) | MAPTRAB9ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL29066479 | 0.81 | RAB9A (0.48) | MAPTPOLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29066482 | 0.81 | RAB9A (0.48) | MAPTPOLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29066486 | 0.80 | NPC1 (0.53) | MAPTPOLBRAB9ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283822-B | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2024-11-15 | — | — | CN | claimed |
| CN-116283822-A | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116283822-B | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-116283822-A | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2023-06-23 | — | — | CN | disclosed |