Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.48 |
| ▸ | NPC1 | O15118 | 9/20 | 0.48 |
| ▸ | GAA | P10253 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29066482 | 1.00 | RAB9A (0.48) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL30421200 | 0.82 | KDM4E (0.60) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL29066492 | 0.82 | KDM4E (0.60) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL29066490 | 0.82 | KDM4E (0.60) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL29066493 | 0.81 | MAPT (0.61) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL29066494 | 0.81 | MAPT (0.61) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL29066480 | 0.79 | MAPT (0.48) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL30421177 | 0.79 | MAPT (0.48) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL29066486 | 0.77 | NPC1 (0.53) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL29066483 | 0.77 | NPC1 (0.53) | RAB9ANPC1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283822-B | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2024-11-15 | — | — | CN | claimed |
| CN-116283822-A | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116283822-B | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-116283822-A | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2023-06-23 | — | — | CN | disclosed |