Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29066495 | 1.00 | KDM4E (0.42) | KDM4EKMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL29066504 | 0.91 | KDM4E (0.42) | KDM4EKMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL29066503 | 0.91 | KDM4E (0.42) | KDM4EKMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL29066480 | 0.85 | MAPT (0.48) | KDM4EKMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL30421177 | 0.85 | MAPT (0.48) | KDM4EKMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL29066478 | 0.85 | MAPT (0.48) | KDM4EKMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL29066494 | 0.75 | MAPT (0.61) | KDM4EKMT2ALMNASMN1; SMN2POLB | |
| SCHEMBL29066493 | 0.75 | MAPT (0.61) | KDM4EKMT2ALMNASMN1; SMN2POLB | |
| SCHEMBL29066490 | 0.72 | KDM4E (0.60) | KDM4EKMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL29066479 | 0.71 | RAB9A (0.48) | KMT2ASMN1; SMN2TDP1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283822-A | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116283822-A | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2023-06-23 | — | — | CN | disclosed |