Methylparaben

Methylparaben

SCHEMBL2906663

COC(=O)c1ccc(O)cc1.OCCOc1ccccc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.72
RAB9A P51151 2/20 0.72
KDM4E B2RXH2 1/20 0.59
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA12 O43570 1/20 0.59
CA7 P43166 1/20 0.59
CA9 Q16790 1/20 0.59
CA14 Q9ULX7 1/20 0.59
GAA P10253 1/20 0.56
ALDH1A1 P00352 3/20 0.56
RECQL P46063 1/20 0.56
CYP19A1 P11511 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64651 0.86 MAPT (0.82) MAPTRAB9AKDM4ECA1CA2
Propylparaben SCHEMBL2849806 0.85 ALDH1A1 (0.68) MAPTRAB9ACA1CA2CA12
Isopropyl 4-Hydroxybenzoate SCHEMBL4729204 0.85 CA12 (0.62) MAPTRAB9AKDM4ECA1CA2
Paraben SCHEMBL7565095 0.84 PKM (0.69) CA1CA2CA12CA7CA9
SCHEMBL5284759 0.84 MAPT (1.00) MAPTRAB9AKDM4ECA1CA2
Butylparaben SCHEMBL27667999 0.84 ESR1 (0.56) MAPTRAB9AKDM4ECA1CA2
Propylparaben SCHEMBL8396726 0.83 MAPT (0.51) MAPTRAB9AKDM4ECA1CA2
SCHEMBL4815928 0.83 MAPT (0.77) MAPTRAB9AKDM4ECA1CA2
SCHEMBL24845112 0.83 MAPT (0.77) MAPTRAB9ACA1CA2CA12
SCHEMBL6539224 0.83 MAPT (0.90) MAPTRAB9AKDM4ECA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107961204-A A kind of snail jade-like stone profit snow flesh facial mask liquid and preparation method thereof 广州柏俐臣化妆品有限公司 2018-04-27 CN claimed
CN-102366397-B Skin-whitening chloasma-reducing skin-brightening composition, skin care product therewith, and preparation method thereof BAOJIAN CHINA COMMODITY CO LTD 2013-01-30 CN claimed
US-20240009105-A1 TETRAPEPTIDE AND COMPOSITIONS COMPRISING TETRAPEPTIDES THE BOOTS COMPANY PLC (GB) 2024-01-11 US disclosed
EP-1491186-B1 Cleaning article of heterogeneous constitution BEIERSDORF AG (DE) 2010-08-11 EP disclosed
EP-1784423-B1 NOVEL PEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAID PEPTIDE CENTRE NAT RECH SCIENT (FR) 2008-10-08 EP disclosed
EP-1602359-A1 Cosmetic or dermatologic impregnated wipes Beiersdorf AG (DE) 2005-12-07 EP disclosed
EP-1210928-B1 Cosmetically or dermatologically impregnated towelettes BEIERSDORF AG (DE) 2005-09-21 EP disclosed
EP-1491186-A2 Cleaning article of heterogeneous constitution Beiersdorf AG (DE) 2004-12-29 EP disclosed
EP-0892632-B1 COMPOSITIONS USEFUL IN THE PHOTOTHERAPEUTIC TREATMENT OF PROLIFERATIVE SKIN DISORDERS ESTEE LAUDER INC (US) 2003-10-29 EP disclosed
EP-1210928-A1 Cosmetically or dermatologically impregnated towelettes Beiersdorf Aktiengesellschaft (DE) 2002-06-05 EP disclosed
EP-1201220-A1 Cosmetic or pharmaceutical compositions containing thermostabilising microcapsules L'OREAL (FR) 2002-05-02 EP disclosed
CN-1327474-A Tenside composition containing gemini tensides and co-amphiphiles and production and use thereof SASOL DEUTSCHE CO LTD (DE) 2001-12-19 CN disclosed
EP-0892632-A4 COMPOSITIONS USEFUL IN THE PHOTOTHERAPEUTIC TREATMENT OF PROLIFERATIVE SKIN DISORDERS ESTEE LAUDER INC (US) 1999-11-24 EP disclosed
US-5885557-A TOPICAL MIXTURE OF 1,3-DIHYDROXYACETONE, A PENETRATION ATTENUATOR AND A CARRIER; RAPID ?SLOUGHING OFF? OF THE INDUCED TAN FROM THE AFFECTED AREAS; PSORIASIS; ECZEMA ESTEE LAUDER INC. (US) 1999-03-23 US disclosed
EP-0892632-A1 COMPOSITIONS USEFUL IN THE PHOTOTHERAPEUTIC TREATMENT OF PROLIFERATIVE SKIN DISORDERS ESTEE LAUDER INC. (US) 1999-01-27 EP disclosed
WO-1997028784-A1 COMPOSITIONS USEFUL IN THE PHOTOTHERAPEUTIC TREATMENT OF PROLIFERATIVE SKIN DISORDERS ESTEE LAUDER INC. (US) 1997-08-14 WO disclosed