Paraben

Paraben

SCHEMBL7565095

O=C(O)c1ccc(O)cc1.OCCOc1ccccc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.69
ALDH1A1 P00352 1/20 0.63
RECQL P46063 1/20 0.63
GAA P10253 1/20 0.63
CYP19A1 P11511 2/20 0.57
NR4A2 P43354 2/20 0.56
NR4A1 P22736 1/20 0.56
NR4A3 Q92570 1/20 0.56
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA3 P07451 1/20 0.53
TYR P14679 1/20 0.53
DRD1 P21728 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL11749646 0.93 PKM (0.79) PKMALDH1A1RECQLGAANR4A2
Phenoxyethanol SCHEMBL7771383 0.90 ALDH1A1 (0.73) PKMALDH1A1RECQLGAANR4A2
Phenoxyethanol SCHEMBL27876997 0.88 ALDH1A1 (0.70) PKMALDH1A1RECQLGAANR4A2
SCHEMBL77587 0.86 PKM (0.71) PKMALDH1A1RECQLGAANR4A2
Methylparaben SCHEMBL2906663 0.84 MAPT (0.72) PKMALDH1A1RECQLGAACYP19A1
Phenoxyethanol SCHEMBL15568699 0.84 ALDH1A1 (0.83) PKMALDH1A1RECQLGAACYP19A1
SCHEMBL8429336 0.82 RARB (0.68) PKMALDH1A1RECQLGAASRD5A2
SCHEMBL1285278 0.82 PKM (1.00) PKMALDH1A1GAANR4A2NR4A1
Salicylic Acid SCHEMBL3184806 0.81 PKM (0.61) PKMALDH1A1RECQLGAANR4A2
2-Phenylphenol SCHEMBL28716069 0.81 PKM (0.61) PKMALDH1A1RECQLGAANR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1201220-A1 Cosmetic or pharmaceutical compositions containing thermostabilising microcapsules L'OREAL (FR) 2002-05-02 EP disclosed
US-5302380-A Containing atactic polypropylene; good adhesion REVLON CONSUMER PRODUCTS CORPORATION (US) 1994-04-12 US disclosed