Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TAF1 | P21675 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21178948 | 0.73 | TNF (0.53) | IMPDH2IMPDH1BRD4TAF1BRPF1 | |
| SCHEMBL30687262 | 0.73 | TNF (0.44) | IMPDH2IMPDH1BRD4TAF1BRPF1 | |
| SCHEMBL22076299 | 0.73 | IMPDH2 (0.39) | IMPDH2IMPDH1BRD4TAF1BRPF1 | |
| SCHEMBL20157532 | 0.72 | IMPDH2 (0.36) | IMPDH2IMPDH1BRD4TAF1BRPF1 | |
| SCHEMBL29492540 | 0.70 | BRD4 (0.40) | IMPDH2IMPDH1BRD4TAF1BRPF1 | |
| SCHEMBL25596753 | 0.70 | NR3C1 (0.40) | IMPDH2IMPDH1BRD4TAF1BRPF1 | |
| SCHEMBL29066861 | 0.69 | DYRK1A (0.44) | IMPDH2IMPDH1CHEK1 | |
| SCHEMBL29361477 | 0.68 | AHR (0.50) | IMPDH2IMPDH1BRD4TAF1BRPF1 | |
| SCHEMBL1420318 | 0.68 | AHR (0.50) | IMPDH2IMPDH1BRD4TAF1BRPF1 | |
| Hydrochloric Acid SCHEMBL29363603 | 0.67 | AHR (0.48) | IMPDH2IMPDH1BRD4TAF1BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693538-A | Pyrazolopyrimidine derivative, and preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2023-09-05 | — | — | CN | disclosed |