SCHEMBL29066993

SCHEMBL29066993

C=Cc1ccccc1C=C.[SiH3]OCCc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
IDO1 P14902 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
ALDH1A1 P00352 2/20 0.36
ALOX5 P09917 1/20 0.36
AKR1B10 O60218 1/20 0.36
AKR1B1 P15121 1/20 0.36
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
HSD17B10 Q99714 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
TDP1 Q9NUW8 3/20 0.35
DRD2 P14416 1/20 0.35
DRD4 P21917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL523683 0.84 CA1 (0.48) CA1CA2CA9HCAR2IDO1
SCHEMBL29066959 0.81 TSHR (0.43) CA1CA2CA9HCAR2IDO1
SCHEMBL296248 0.79 ALDH1A1 (0.38) ALDH1A1HPGDSMN1; SMN2
SCHEMBL29241974 0.78 CYP11B1 (0.46) IDO1NPC1RAB9AALDH1A1ALOX5
SCHEMBL8940327 0.75 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10TDP1SMN1; SMN2
SCHEMBL28340922 0.75 ALDH1A1 (0.46) CA1CA9ALDH1A1TDP1
SCHEMBL29066951 0.74 ALDH1A1 (0.48) ALDH1A1HPGDALOX12CASP1HSD17B10
SCHEMBL4908049 0.74 CA1 (0.39) CA1CA2CA9HCAR2IDO1
SCHEMBL11234470 0.72 TSHR (0.65) CA1CA2CA9IDO1ALDH1A1
SCHEMBL27447290 0.72 TSHR (0.46) CA1CA2CA9HCAR2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN disclosed