Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569788 | 1.00 | KMT2A (0.59) | KMT2AAPEX1LMNAMAPTHTT | |
| SCHEMBL10889755 | 0.91 | KMT2A (0.69) | KMT2AAPEX1LMNAMAPTHTT | |
| SCHEMBL25969064 | 0.86 | KMT2A (0.59) | KMT2AAPEX1LMNAMAPTHTT | |
| SCHEMBL29067150 | 0.84 | TSHR (0.54) | KMT2AMAPTHTTTSHRKDM4E | |
| SCHEMBL10158103 | 0.84 | HTT (0.68) | KMT2AAPEX1LMNAMAPTHTT | |
| SCHEMBL13164083 | 0.82 | KMT2A (0.63) | KMT2AMAPTHTTTSHRMAPK1 | |
| SCHEMBL5849754 | 0.81 | HTT (0.63) | KMT2AAPEX1LMNAMAPTHTT | |
| SCHEMBL9695573 | 0.81 | HTT (0.63) | KMT2AAPEX1LMNAMAPTHTT | |
| SCHEMBL6273378 | 0.81 | HTT (0.86) | KMT2AAPEX1LMNAMAPTHTT | |
| SCHEMBL14483855 | 0.81 | MAPK1 (0.50) | KMT2AAPEX1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116712561-A | Antibody-drug conjugates containing an N-methyleneamide linker | 杭州爱科瑞思生物医药有限公司 | 2023-09-08 | — | — | CN | disclosed |