SCHEMBL29067147

SCHEMBL29067147

CCOC(C)OC(C)C(=O)O.NC(=O)CBr

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
TRPA1 O75762 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6889186 0.87 LMNA (0.48) LMNA
SCHEMBL4377419 0.87 LMNA (0.48) LMNA
SCHEMBL6889182 0.87 LMNA (0.48) LMNA
SCHEMBL10633540 0.85 LMNA (0.46) LMNA
SCHEMBL28938350 0.83 LMNA (0.44) LMNA
Bromoacetic Acid SCHEMBL1982827 0.73 LMNA (0.57) LMNATRPA1ALDH1A1
Carbamic Acid SCHEMBL5387548 0.72 LMNA (0.63) LMNAALDH1A1
SCHEMBL27154341 0.71 LMNA (0.48) LMNAALDH1A1
Urea SCHEMBL1377094 0.70 LMNA (0.67) LMNAALDH1A1
SCHEMBL142064 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116712561-A Antibody-drug conjugates containing an N-methyleneamide linker 杭州爱科瑞思生物医药有限公司 2023-09-08 CN disclosed