Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4377419 | 1.00 | LMNA (0.48) | LMNATP53THRBPPARACHRM1 | |
| SCHEMBL6889182 | 1.00 | LMNA (0.48) | LMNATP53THRBPPARACHRM1 | |
| SCHEMBL10633540 | 0.98 | LMNA (0.46) | LMNATP53THRBPPARACHRM1 | |
| SCHEMBL28938350 | 0.96 | LMNA (0.44) | LMNAPPARA | |
| SCHEMBL29067147 | 0.87 | LMNA (0.37) | LMNA | |
| SCHEMBL27154341 | 0.82 | LMNA (0.48) | LMNATHRB | |
| SCHEMBL8665797 | 0.80 | LMNA (0.43) | LMNATP53THRBPPARACHRM1 | |
| SCHEMBL15137737 | 0.80 | — | — | |
| SCHEMBL142064 | 0.80 | — | — | |
| SCHEMBL3141884 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720463-B1 | REDUCING AN ALKYLHYDROXYESTER WITH EASY TO HANDLE SODIUM BOROHYDRIDE; MAINTAINING OPTICAL ACTIVITY | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-04-13 | — | — | US | disclosed |
| EP-1146032-A1 | PROCESS FOR THE PRODUCTION OF ALKANEDIOL DERIVATIVES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-10-17 | — | — | EP | disclosed |