Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067310 | 0.98 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL27765408 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL12744123 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL12744144 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL14575736 | 0.71 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL29177386 | 0.70 | POLB (0.44) | ALDH1A1MAPTGAAKDM4EPOLB | |
| SCHEMBL20176409 | 0.70 | HRH3 (0.57) | ALDH1A1MAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL21638175 | 0.69 | SCD (0.53) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL4035553 | 0.69 | HDAC2 (0.40) | MAPTLMNATMPRSS15HDAC3HDAC4 | |
| SCHEMBL30532412 | 0.68 | TMPRSS15 (0.76) | TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507607-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2023-07-28 | — | — | CN | disclosed |