Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29224913 | 0.95 | ALDH1A1 (0.40) | POLBSMN1; SMN2ALDH1A1MAPTAOC3 | |
| SCHEMBL186136 | 0.85 | ALDH1A1 (0.46) | POLBSMN1; SMN2ALDH1A1MAPTAOC3 | |
| SCHEMBL28941048 | 0.84 | POLB (0.58) | POLBALDH1A1AOC3KDM4EPTPN11 | |
| SCHEMBL184999 | 0.83 | ALDH1A1 (0.47) | POLBSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL29177274 | 0.80 | UBE2T (0.51) | POLBSMN1; SMN2ALDH1A1MAPTAOC3 | |
| SCHEMBL28284732 | 0.78 | UBE2T (0.53) | POLBSMN1; SMN2ALDH1A1MAPTAOC3 | |
| SCHEMBL4790004 | 0.77 | POLB (0.49) | POLBSMN1; SMN2ALDH1A1MAPTAOC3 | |
| SCHEMBL29177455 | 0.76 | JAK2 (0.41) | ALDH1A1MAPTTP53MAPK1ACACB | |
| SCHEMBL20917117 | 0.75 | POLB (0.50) | POLBSMN1; SMN2ALDH1A1MAPTAOC3 | |
| SCHEMBL29177328 | 0.74 | UBE2T (0.49) | POLBALDH1A1MAPTAOC3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |