Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067512 | 0.77 | RAB9A (0.38) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL29067523 | 0.76 | IDO1 (0.32) | CA12CA1CA2CA9 | |
| SCHEMBL29067511 | 0.76 | TGM2 (0.42) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL29067540 | 0.76 | MEN1 (0.37) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL29067518 | 0.75 | TDP1 (0.40) | MAPTSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL29067521 | 0.75 | TGM2 (0.46) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL10929180 | 0.73 | MAPT (0.46) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL10055051 | 0.71 | RXFP1 (0.56) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL10601664 | 0.71 | MAPT (0.54) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL28927497 | 0.68 | MAPT (0.47) | MAPTRAB9AKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462598-B | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2024-08-09 | — | — | CN | disclosed |
| CN-116462598-A | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2023-07-21 | — | — | CN | disclosed |