Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067512 | 0.82 | RAB9A (0.38) | MEN1KMT2ACA2CA9NPC1 | |
| SCHEMBL29067523 | 0.81 | IDO1 (0.32) | CA2CA9 | |
| SCHEMBL29067511 | 0.81 | TGM2 (0.42) | MEN1KMT2AMAPTMAPK1CA2 | |
| SCHEMBL29067518 | 0.81 | TDP1 (0.40) | MEN1KMT2AMAPTMAPK1CA9 | |
| SCHEMBL29067521 | 0.77 | TGM2 (0.46) | MEN1KMT2AMAPTMAPK1NPSR1 | |
| SCHEMBL29067524 | 0.76 | MAPT (0.44) | MEN1KMT2AHTTMAPTMAPK1 | |
| SCHEMBL29067546 | 0.71 | KCNQ2 (0.38) | MEN1KMT2AHTTMAPTMAPK1 | |
| SCHEMBL1167951 | 0.71 | ALDH1A1 (0.50) | MEN1KMT2AHTTMAPTMAPK1 | |
| SCHEMBL17604274 | 0.71 | ALDH1A1 (0.50) | MEN1KMT2AHTTMAPTMAPK1 | |
| SCHEMBL29067507 | 0.70 | ACP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462598-B | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2024-08-09 | — | — | CN | disclosed |
| CN-116462598-A | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2023-07-21 | — | — | CN | disclosed |