Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452244 | 1.00 | BRD4 (0.37) | BRD4NR1H2GAAAPLNRARG1 | |
| SCHEMBL29067925 | 1.00 | BRD4 (0.37) | BRD4NR1H2GAAAPLNRARG1 | |
| SCHEMBL15106713 | 0.82 | BRD4 (0.43) | BRD4NR1H2GAAAPLNREGFR | |
| Hydrochloric Acid SCHEMBL29180511 | 0.81 | EPHX2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL29180515 | 0.81 | EPHX2 (0.30) | — | |
| SCHEMBL29067981 | 0.79 | SLC6A1 (0.50) | APLNRARG1SLC6A1GABRA5GABRB2 | |
| SCHEMBL29067977 | 0.79 | SLC6A1 (0.50) | APLNRARG1SLC6A1GABRA5GABRB2 | |
| SCHEMBL956931 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL29180517 | 0.77 | SLC6A12 (0.48) | APLNRARG1SLC6A1GABRA5GABRB2 | |
| Hydrochloric Acid SCHEMBL29180516 | 0.77 | SLC6A12 (0.48) | APLNRARG1SLC6A1GABRA5GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |