SCHEMBL29068282

SCHEMBL29068282

NCC(=O)Oc1ccc(C(F)(F)F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.59
ALDH1A1 P00352 1/20 0.50
PRSS1 P07477 1/20 0.48
ACR P10323 1/20 0.48
MAOB P27338 5/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
AOC3 Q16853 1/20 0.45
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
PTPN1 P18031 1/20 0.42
GSK3B P49841 1/20 0.42
CYP11B1 P15538 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9492305 0.85 KIF11 (0.58) KIF11ALDH1A1PRSS1ACRMAOB
SCHEMBL25311037 0.85 KIF11 (0.58) KIF11ALDH1A1PRSS1ACRMAOB
Trifluoroacetic Acid SCHEMBL3833089 0.83 CA12 (0.43) KIF11ALDH1A1CA1CA2CA9
SCHEMBL29000619 0.81 CES2 (0.44) KIF11ALDH1A1CES2MEN1LMNA
SCHEMBL27711454 0.81 MAPT (0.53) ALDH1A1PRSS1ACRMAOBCA1
SCHEMBL9805986 0.81 KMT2A (0.44) KIF11ALDH1A1MAOBAOC3MEN1
SCHEMBL1294868 0.81 KMT2A (0.58) KIF11ALDH1A1PRSS1ACRMAOB
SCHEMBL2352342 0.81 KIF11 (0.54) KIF11ALDH1A1PRSS1ACRMAOB
SCHEMBL9492308 0.80 KIF11 (0.53) KIF11ALDH1A1PRSS1ACRMAOB
SCHEMBL13724130 0.80 KIF11 (0.53) KIF11ALDH1A1PRSS1ACRMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116554050-A Amide phenol derivative and application thereof 四川大学 2023-08-08 CN disclosed