Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22441384 | 0.83 | KMT2A (0.61) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL1908559 | 0.80 | ABL1 (0.65) | — | |
| SCHEMBL4908166 | 0.78 | GRM5 (0.61) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9194129 | 0.76 | KMT2A (0.72) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL18748195 | 0.75 | TP53 (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL1996429 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL26436195 | 0.74 | RAB9A (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL21068015 | 0.74 | CSF1R (0.81) | ALDH1A1KDM4EMAPTMAPK1HSD17B10 | |
| SCHEMBL25884032 | 0.74 | KDM4E (0.65) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL19073296 | 0.74 | CA12 (0.56) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872279-B | High-yield synthesis method of nilotinib | 安徽峆一药业股份有限公司 | 2023-09-08 | — | — | CN | disclosed |