Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068347 | 0.89 | MMP13 (0.50) | MMP13MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL23212045 | 0.83 | LIPE (0.41) | HDAC1HDAC2MMP13MEN1KMT2A | |
| SCHEMBL21381989 | 0.83 | LIPE (0.41) | HDAC1HDAC2MMP13MEN1KMT2A | |
| SCHEMBL21384664 | 0.80 | HDAC1 (0.46) | HDAC1HDAC2MMP13MEN1KMT2A | |
| SCHEMBL23211978 | 0.80 | HDAC1 (0.46) | HDAC1HDAC2MMP13MEN1KMT2A | |
| SCHEMBL16232117 | 0.79 | HDAC2 (0.47) | HDAC1HDAC2MMP13MEN1KMT2A | |
| SCHEMBL29977752 | 0.79 | HDAC2 (0.47) | HDAC1HDAC2MMP13MEN1KMT2A | |
| SCHEMBL31668195 | 0.76 | HDAC1 (0.43) | HDAC1HDAC2MMP13MEN1KMT2A | |
| SCHEMBL1122151 | 0.74 | MMP13 (0.51) | HDAC1HDAC2MMP13MEN1KMT2A | |
| SCHEMBL7417677 | 0.74 | MMP13 (0.53) | MMP13MEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |