Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19375935 | 0.85 | HTR3A (0.56) | HTR3A | |
| SCHEMBL24449304 | 0.81 | PTGS1 (0.44) | — | |
| SCHEMBL29750537 | 0.81 | PTGS1 (0.44) | — | |
| SCHEMBL2885151 | 0.81 | HTR3A (0.46) | HTR3A | |
| Hydrochloric Acid SCHEMBL941521 | 0.79 | NPC1 (0.47) | HTR3A | |
| SCHEMBL30567970 | 0.79 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL21381590 | 0.79 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL25257284 | 0.78 | KMT2A (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL17729503 | 0.76 | OPRM1 (0.40) | — | |
| SCHEMBL20757564 | 0.76 | CHRNB2 (0.43) | CHRNB2CHRNA4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |