Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391003 | 1.00 | MAPT (0.58) | MAPTLMNATSHRHPGDHTT | |
| SCHEMBL31494353 | 0.79 | SMN1; SMN2 (0.42) | MAPTLMNATSHRHPGDHTT | |
| SCHEMBL27218795 | 0.79 | SMN1; SMN2 (0.42) | MAPTLMNATSHRHPGDHTT | |
| SCHEMBL27218802 | 0.79 | ALDH1A1 (0.42) | MAPTLMNATSHRHPGDHTT | |
| SCHEMBL30567828 | 0.79 | SMN1; SMN2 (0.43) | MAPTLMNATSHRHPGDHTT | |
| SCHEMBL27218831 | 0.75 | ADORA2A (0.40) | MAPTLMNATSHRHPGDHTT | |
| SCHEMBL31494398 | 0.75 | ADORA2A (0.40) | MAPTLMNATSHRHPGDHTT | |
| SCHEMBL22556713 | 0.73 | MEN1 (0.46) | MAPTLMNAMEN1KMT2ATP53 | |
| SCHEMBL27218643 | 0.72 | MEN1 (0.36) | MAPTLMNATSHRHPGDHTT | |
| SCHEMBL31494377 | 0.72 | ADORA2A (0.39) | MAPTLMNATSHRHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745289-A | Agonists of free fatty acid receptor 1 and their use in diseases associated with said receptor | 奥洛治疗有限公司 | 2023-09-12 | — | — | CN | disclosed |