SCHEMBL29068596

SCHEMBL29068596

CCCOS(=O)(=O)c1ccc(C)c(-c2cccc(C(F)(F)F)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.42
SLC1A2 P43004 2/20 0.42
SLC1A1 P43005 2/20 0.42
RAF1 P04049 3/20 0.41
BRAF P15056 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
PTGS2 P35354 2/20 0.39
PTGDR2 Q9Y5Y4 2/20 0.39
IDH1 O75874 1/20 0.39
FFAR1 O14842 1/20 0.38
CDK1 P06493 1/20 0.38
CCNB1 P14635 1/20 0.38
CCNA2 P20248 1/20 0.38
CDK2 P24941 1/20 0.38
CDK7 P50613 1/20 0.38
CCNH P51946 1/20 0.38
CCNA1 P78396 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29068583 0.77 PTGS2 (0.40) CYP1A2CYP3A4CYP2C9CYP2C19PTGS2
SCHEMBL29068571 0.74 PTGS2 (0.42) PTGS2FFAR4KDM4E
SCHEMBL28719323 0.74 KMT2A (0.42) PTGS2CA1CA2KMT2ASCN9A
SCHEMBL26375402 0.73 SLC1A3 (0.50) SLC1A3SLC1A2SLC1A1RAF1BRAF
SCHEMBL23152484 0.73 PARP10 (0.38) RAF1PTGS2
SCHEMBL21834496 0.72 CYP1A2 (0.44) CYP1A2CYP3A4CYP2C9CYP2C19PTGS2
SCHEMBL28602434 0.71 PIK3CD (0.41) CA2
SCHEMBL12629284 0.71 SLC1A3 (0.48) SLC1A3SLC1A2SLC1A1RAF1BRAF
SCHEMBL14228194 0.70 ALDH1A1 (0.42) CA1CA2KMT2A
SCHEMBL10094660 0.70 SLC1A3 (0.47) SLC1A3SLC1A2SLC1A1RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116745304-A IP4-4,6 substituted derivative compounds 萨尼菲特治疗有限公司 2023-09-12 CN disclosed