Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068583 | 0.88 | PTGS2 (0.40) | PTGS2PTGS1RAPGEF4PKMLMNA | |
| SCHEMBL25702737 | 0.81 | PKM (0.53) | PKMLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL28602434 | 0.81 | PIK3CD (0.41) | — | |
| SCHEMBL7624637 | 0.77 | PTGS2 (0.48) | PTGS2PTGS1RAPGEF4PKMFFAR4 | |
| SCHEMBL28427488 | 0.77 | CA2 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8128437 | 0.76 | PTGS2 (0.47) | PTGS2PTGS1RAPGEF4PKMFFAR4 | |
| SCHEMBL23152484 | 0.75 | PARP10 (0.38) | PTGS2PTGS1MAPK14 | |
| SCHEMBL7372817 | 0.75 | GSTP1 (0.46) | — | |
| SCHEMBL29068596 | 0.74 | SLC1A3 (0.42) | PTGS2FFAR4KDM4E | |
| SCHEMBL29285398 | 0.74 | LMNA (0.41) | RAPGEF4PKMLMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745304-A | IP4-4,6 substituted derivative compounds | 萨尼菲特治疗有限公司 | 2023-09-12 | — | — | CN | disclosed |