Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20944057 | 0.81 | KDM4E (0.49) | KDM4ESTAT3HIF1APLAUF2 | |
| SCHEMBL7279246 | 0.81 | MAPT (0.52) | KDM4ESTAT3HIF1ANR4A2MAPT | |
| SCHEMBL31410088 | 0.81 | PLAU (0.45) | KDM4EPLAUMAPTALDH1A1LMNA | |
| SCHEMBL22116876 | 0.80 | KDM4E (0.47) | KDM4ESTAT3HIF1ANR4A2PLAU | |
| SCHEMBL754063 | 0.79 | ATM (0.46) | KDM4EPLAUMAPTALDH1A1CYP1A2 | |
| SCHEMBL7288685 | 0.79 | SMN1; SMN2 (0.53) | KDM4ESTAT3HIF1APLAUF2 | |
| SCHEMBL22116806 | 0.78 | KDM4E (0.45) | KDM4ESTAT3HIF1ANR4A2PLAU | |
| SCHEMBL28584809 | 0.76 | ALDH1A1 (0.49) | KDM4EPLAUALDH1A1LMNAPOLB | |
| SCHEMBL23580382 | 0.75 | NR4A2 (0.43) | KDM4ESTAT3HIF1ANR4A2MAPT | |
| SCHEMBL1493848 | 0.75 | DYRK1A (0.43) | KDM4EMAPTALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490505-A | MNK inhibitors | 和博医药有限公司 | 2023-07-25 | — | — | CN | disclosed |