SCHEMBL29071045

SCHEMBL29071045

Cc1ccc2c(c1)c(C)nc1ccc(Cl)cc12

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 1/20 0.51
LMNA P02545 3/20 0.50
MPO P05164 2/20 0.48
KDM4E B2RXH2 5/20 0.45
KMT2A Q03164 3/20 0.44
DHODH Q02127 2/20 0.44
MEN1 O00255 2/20 0.44
FABP3 P05413 1/20 0.44
FABP4 P15090 1/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 2/20 0.44
PKM P14618 1/20 0.43
RAD52 P43351 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
USP2 O75604 1/20 0.42
HSD17B10 Q99714 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30659916 1.00 HSP90AB1 (0.51) HSP90AB1LMNAMPOKDM4EKMT2A
SCHEMBL29071047 0.89 KDM4E (0.53) LMNAKDM4EKMT2AMEN1ALDH1A1
SCHEMBL30659922 0.89 KDM4E (0.53) LMNAKDM4EKMT2AMEN1ALDH1A1
SCHEMBL21244190 0.82 GPR3 (0.62) HSP90AB1LMNAMPOKDM4EKMT2A
SCHEMBL5212065 0.81 GPR3 (0.66) MPOKDM4EKMT2AMEN1FABP3
SCHEMBL30659937 0.81 GPR3 (0.66) MPOKDM4EKMT2AMEN1FABP3
SCHEMBL28732550 0.80 LMNA (0.49) HSP90AB1LMNAMPOKDM4EKMT2A
SCHEMBL22791812 0.79 LMNA (0.50) HSP90AB1LMNAMPOKDM4EKMT2A
SCHEMBL12593259 0.77 GPR3 (0.48) LMNAKDM4EKMT2AMEN1ALDH1A1
SCHEMBL3259024 0.77 GPR3 (0.70) LMNAKDM4EKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730916-A Method for synthesizing 6-methylphenidate compound by photocatalysis 安徽理工大学 2023-09-12 CN disclosed