⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290725 | 0.78 | — | — | |
| SCHEMBL859923 | 0.76 | — | — | |
| SCHEMBL2456394 | 0.76 | — | — | |
| SCHEMBL10679132 | 0.76 | — | — | |
| SCHEMBL18506861 | 0.76 | — | — | |
| SCHEMBL858586 | 0.76 | — | — | |
| SCHEMBL863450 | 0.76 | ALDH1A1 (0.56) | — | |
| SCHEMBL680649 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL5010896 | 0.74 | — | — | |
| SCHEMBL26118223 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716320-B2 | Antibacteriall heterocyclic ureas | REPLIDYNE, INC. (US) | 2014-05-06 | — | — | US | claimed |
| US-20080207703-A1 | Antibacterial heterocyclic ureas | REPLIDYNE, INC. (US) | 2008-08-28 | — | — | US | claimed |
| US-7402606-B2 | Derivatives of 1-(oxoaminoacetyl) pentylcarbamate as cathepsin K inhibitors for the treatment of bone loss | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-22 | — | — | US | claimed |
| WO-2008011191-A1 | ANTIBACTERIAL HETEROCYCLIC UREAS | REPLIDYNE, INC. (US) | 2008-01-24 | — | — | WO | claimed |
| US-20050245596-A1 | Derivatives of 1-(oxoaminoacetyl) pentylcarbamate as cathepsin k inhibitors for the treatment of bone loss | SMITHKLINE BEECHAM CORPORATION | 2005-11-03 | — | — | US | claimed |
| EP-1494663-A1 | DERIVATIVES OF 1-(OXOAMINOACETYL) PENTYLCARBAMATE AS CATHEPSIN K INHIBITORS FOR THE TREATMENT OF BONE LOSS | SmithKline Beecham Corporation (US) | 2005-01-12 | — | — | EP | claimed |
| EP-1073428-B1 | DIHYDROXYPHENYL DERIVATIVES FOR HEPATOPROTECTION AND TREATMENT OF LIVER DISEASES | CHOONGWAE PHARMA CO LTD (KR) | 2004-10-27 | — | — | EP | claimed |
| WO-2003086385-A1 | DERIVATIVES OF 1-(OXOAMINOACETYL) PENTYLCARBAMATE AS CATHEPSIN K INHIBITORS FOR THE TREATMENT OF BONE LOSS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-10-23 | — | — | WO | claimed |
| WO-2002040449-A1 | DIHYDROISOQUINOLINES AS NOVEL PHOSPHODIESTERASE INHIBITORS | ALTANA PHARMA AG (DE) | 2002-05-23 | — | — | WO | claimed |
| EP-0328830-B1 | 4-Heteropentacyclic-4- N-(phenyl)amido piperidine compounds | OHMEDA PHARMA PROD (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0160422-B1 | N-ARYL-N-(4-PIPERIDINYL)AMIDES AND PHARMACEUTICAL COMPOSITIONS AND METHODS EMPLOYING SUCH COMPOUNDS | Anaquest, Inc. (US) | 1992-01-08 | — | — | EP | claimed |
| EP-0328830-A1 | 4-Heteropentacyclic-4- N-(phenyl)amido piperidine compounds | Ohmeda Pharmaceutical Products Division Inc. (US) | 1989-08-23 | — | — | EP | claimed |
| EP-0131374-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PENEM DERIVATIVES | PFIZER INC. (US) | 1988-11-23 | — | — | EP | claimed |
| US-4725678-A | ANTIBIOTICS | PFIZER INC. (US) | 1988-02-16 | — | — | US | claimed |
| US-4619783-A | BACTERICIDES | PFIZER INC. (US) | 1986-10-28 | — | — | US | claimed |
| US-4595539-A | Containing acid or ester groups and sulfur | PFIZER INC. (US) | 1986-06-17 | — | — | US | claimed |
| US-4584303-A | ANALGESICS | THE BOC GROUP, INC. (US) | 1986-04-22 | — | — | US | claimed |
| EP-0160422-A1 | N-Aryl-N-(4-Piperidinyl)amides and pharmaceutical compositions and methods employing such compounds | Anaquest, Inc. (US) | 1985-11-06 | — | — | EP | claimed |
| EP-0131374-A1 | Process and intermediates for the preparation of penem derivatives | PFIZER INC. (US) | 1985-01-16 | — | — | EP | claimed |
| EP-0128725-A1 | Preparation of penem derivatives | PFIZER INC. (US) | 1984-12-19 | — | — | EP | claimed |