⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clomethiazole SCHEMBL35223 | 0.82 | — | — | |
| Clomethiazole SCHEMBL1606752 | 0.80 | ALDH1A1 (0.96) | — | |
| Cloprothiazole SCHEMBL1069474 | 0.80 | ALDH1A1 (0.81) | — | |
| Methylene Chloride SCHEMBL28269018 | 0.80 | ALDH1A1 (0.62) | — | |
| SCHEMBL290725 | 0.78 | — | — | |
| SCHEMBL1366919 | 0.76 | — | — | |
| SCHEMBL2456394 | 0.76 | — | — | |
| SCHEMBL290723 | 0.76 | — | — | |
| SCHEMBL18506861 | 0.76 | — | — | |
| SCHEMBL13066854 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005121-B1 | PROCESS FOR STABILISATION OF 4-METHYL-5-(2'-CHLORETHYL)-THIAZOL | PHARMACEUTICAL LICENCES COMPANY LTD. (CH) | 1982-10-13 | — | — | EP | claimed |
| WO-2026041663-A1 | P2X7 RECEPTOR ANTAGONISTS | BREYE THERAPEUTICS APS (DK) | 2026-02-26 | — | — | WO | disclosed |
| CN-116332955-B | Cefditoren pivoxil Process for the preparation of intermediates | 深圳六合六医疗器械有限公司 | 2025-06-03 | — | — | CN | disclosed |
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | GFB (ABC), LLC | 2023-06-29 | — | — | US | disclosed |
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | GFB (ABC), LLC | 2023-06-29 | — | — | US | disclosed |
| CN-116332955-A | Preparation method of cefditoren pivoxil intermediate | 深圳六合六医疗器械有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-11623919-B2 | Heterocyclic P2X7 antagonists | BREYE THERAPEUTICS APS (DK) | 2023-04-11 | — | — | US | disclosed |
| EP-3619200-A1 | HETEROCYCLIC P2X7 ANTAGONISTS | AXXAM S.p.A. (IT) | 2020-03-11 | — | — | EP | disclosed |
| US-20200055831-A1 | HETEROCYCLIC P2X7 ANTAGONISTS | BREYE THERAPEUTICS APS (DK) | 2020-02-20 | — | — | US | disclosed |
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |
| US-5001138-A | Insecticides | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4845106-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |
| US-4665066-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |
| EP-0005121-B1 | PROCESS FOR STABILISATION OF 4-METHYL-5-(2'-CHLORETHYL)-THIAZOL | PHARMACEUTICAL LICENCES COMPANY LTD. (CH) | 1982-10-13 | — | — | EP | disclosed |
| EP-0005121-A2 | Process for stabilisation of 4-methyl-5-(2'-chlorethyl)-thiazol | PHARMACEUTICAL LICENCES COMPANY LTD. (CH) | 1979-10-31 | — | — | EP | disclosed |