Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 4/20 | 0.62 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.62 |
| ▸ | PPARG | P37231 | 14/20 | 0.56 |
| ▸ | PPARA | Q07869 | 12/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28982634 | 0.90 | SRR (0.58) | SRRPSAT1PPARGPPARAPTGS1 | |
| SCHEMBL114063 | 0.82 | SRR (0.55) | SRRPSAT1PPARGPPARAFFAR1 | |
| SCHEMBL28558472 | 0.80 | PPARG (0.53) | PPARGPPARA | |
| SCHEMBL28558470 | 0.80 | PPARG (0.53) | PPARGPPARA | |
| SCHEMBL28377998 | 0.79 | SRR (0.53) | SRRPSAT1PPARGPPARAFFAR1 | |
| SCHEMBL28549393 | 0.77 | LDHA (0.56) | PPARGPPARAHTT | |
| SCHEMBL7454107 | 0.77 | SRR (0.51) | SRRPSAT1PPARGPPARAPTGS1 | |
| SCHEMBL7454461 | 0.77 | SRR (0.51) | SRRPSAT1PPARGPPARAPTGS1 | |
| SCHEMBL7454095 | 0.77 | SRR (0.51) | SRRPSAT1PPARGPPARAPTGS1 | |
| SCHEMBL17205184 | 0.77 | SRR (0.54) | SRRPSAT1PPARGPPARAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783183-A | 1- (2- (4-cyclopropyl-1H-1, 2, 3-triazol-1-yl) acetyl) -4-hydroxy-N- (benzyl) pyrrolidine-2-carboxamide derivatives as VHL inhibitors for the treatment of anemia and cancer | 基因泰克公司 | 2023-09-19 | — | — | CN | disclosed |